Title of article
Dibutyl 2-(trifluoromethyl)cyclopropylboronate as a useful (trifluoromethyl)cyclopropyl donor: application to antagonists of TRPV1
Author/Authors
Duncton، نويسنده , , Matthew A.J. and Ayala، نويسنده , , Leticia and Kaub، نويسنده , , Carl and Janagani، نويسنده , , Satyanarayana and Edwards، نويسنده , , William T. and Orike، نويسنده , , Nina and Ramamoorthy، نويسنده , , Krithika and Kincaid، نويسنده , , John and Kelly، نويسنده , , Michael G.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
1009
To page
1011
Abstract
Dibutyl-2-(trifluoromethyl)cyclopropylboronate 2, available in one step from commercially available reagents, serves as a useful (trifluoromethyl)cyclopropylating reagent by participating in a palladium-catalyzed Suzuki coupling. The use of boronate ester 2 in medicinal chemistry was exemplified by preparation of TRPV1 receptor antagonists.
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871132
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