Title of article
Carboxylation reaction of a highly functionalized vinylic anion: a case of unexpected stability and reactivity
Author/Authors
Gomez، نويسنده , , Laurent and Wu، نويسنده , , Jiejun and Mani، نويسنده , , Neelakandha S. and Basu، نويسنده , , Sudip and Moravek، نويسنده , , Josef and Breitenbucher، نويسنده , , J. Guy، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
1110
To page
1113
Abstract
Attempts to prepare JNJ 26273364, a highly functionalized pyrazole-based CCK1 receptor antagonist, using a carboxylation reaction led to a series of unexpected results. This work demonstrated the unique reactivity and stability of the highly functionalized Z-alkene functionality present around the pyrazole.
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871215
Link To Document