Title of article
Stereoselective synthesis of dendrobate alkaloid (+)-241D and its C-4 epimer
Author/Authors
G. and Sateesh Chandra Kumar، نويسنده , , R. and Venkateswar Reddy، نويسنده , , G. and Shankaraiah، نويسنده , , G. and Suresh Babu، نويسنده , , K. and Madhusudana Rao، نويسنده , , J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
1114
To page
1116
Abstract
An efficient stereoselective synthesis of dendrobate alkaloid (+)-241D and its C-4 epimer was achieved from the inexpensive, commercially available starting material decanal (10) in an overall yield of 21.9% and 21.1%, respectively. This synthesis utilizes the key steps of Maruoka asymmetric allylation, one-pot epoxidation followed by nucleophilic addition of an organomagnesium reagent (Forsyth’s protocol) and subsequent functional group transformations.
Keywords
piperidine alkaloids , sharpless asymmetric dihydroxylation , Alkaloid (+)-241D , Wacker oxidation
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871218
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