Title of article
DMAP-catalyzed synthesis of 2-oxazolidinones from corresponding halohydrins using KOCN/DMF
Author/Authors
Chinnam Naidu، نويسنده , , K. and Ravi Babu، نويسنده , , G. and Gangaiah، نويسنده , , L. and Mukkanti، نويسنده , , K. and Madhusudhan، نويسنده , , G.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
1226
To page
1229
Abstract
We report facile and simple synthesis of a variety of 2-oxazolidinones from the corresponding halohydrins by reaction with KOCN in DMF catalyzed by DMAP. DMAP and temperature play key roles in enriching the yield of 2-oxazolidinones. A few examples in this Letter are applicable to pharmaceutically important processes.
Keywords
Linezolid , Halohydrin , KOCN , DMAP , 2-Oxazolidinone
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871289
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