Title of article
An enantioselective synthesis of the bicyclic core of the marine natural product awajanomycin
Author/Authors
Pritchard، نويسنده , , Deiniol R. and Wilden، نويسنده , , Jonathan D.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
1819
To page
1821
Abstract
A concise stereoselective synthesis of the N-benzylated bicyclic core of the marine natural product awajanomycin is described starting with naturally occurring l-alanine. Key steps in the synthesis include a ring-closing metathesis to establish a δ-lactam ring followed by a stereoselective hydroxylation to instal the quaternary centre.
Keywords
ring-closing metathesis , Acremonium sp. , ?-Lactam , Diastereoselective hydroxylation
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1871641
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