Title of article
Application of desymmetrization protocol for the formal total synthesis of emericellamide B
Author/Authors
Mohapatra، نويسنده , , Debendra K. and Samad Hossain، نويسنده , , Sk. and Dhara، نويسنده , , Santu and Yadav، نويسنده , , J.S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
4
From page
3079
To page
3082
Abstract
A highly convergent formal total synthesis of emericellamide B, a 19-membered antibacterial depsipeptide is described. The key feature of the strategy is the generation of four stereogenic centers from a bicyclic precursor via desymmetrization technique and utilization for emericellamide B and related natural product synthesis.
Keywords
Emericellamide B , cytotoxicity , desymmetrization , Barton-McCombie reaction , Wittig homologation
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1872270
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