Title of article
BF3-promoted synthesis of spiroindenyl heterocycles
Author/Authors
Chang، نويسنده , , Meng-Yang and Lin، نويسنده , , Chung-Han and Chen، نويسنده , , Yeh-Long and Hsu، نويسنده , , Ru-Ting and Chang، نويسنده , , Ching-Yao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
5
From page
3154
To page
3158
Abstract
An easy and straightforward synthesis of spiroindenyl heterocycles by the repeated treatment of boron trifluoride etherate (BF3-OEt2) is reported. The overall transformation from ketones 1 to spiro-fused indenes 3 proceeds via Wittig olefination, deconjugation, Grignard addition, and intramolecular electrophilic cyclization in moderate yields. It presents a novel rearrangement reaction catalyzed by boron trifluoride etherate and broadens the scope of application.
Keywords
Boron trifluoride etherate , Rearrangement , Spiroindenyl heterocycles
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1872291
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