Title of article
Synthesis of substituted N-hydroxyureas via the in situ generation of t-butoxy isocyanate
Author/Authors
Krause، نويسنده , , Josef G. and Leskiw، نويسنده , , Brian D. and Emery، نويسنده , , Michelle L. and McGahan، نويسنده , , Megan E. and McCourt، نويسنده , , Mary P. and Priefer، نويسنده , , Ronny، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
3568
To page
3570
Abstract
Treatment of primary and secondary amines with tert-butylmesitylenesulfonoxycarbamate and a base afforded tert-butoxyurea, which when treated with an acid ultimately yielded substituted N-hydroxyureas. It is proposed that this proceeded via the generation of t-butoxy isocyanate in situ. This method allows for the synthesis of both mono and disubstituted N-hydroxyureas.
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1872662
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