Title of article
Efficient double bond migration of allylbenzenes catalyzed by Pd(OAc)2–HFIP system with unique substituent effect
Author/Authors
Nishiwaki، نويسنده , , Nagatoshi and Kamimura، نويسنده , , Ryuichiro and Shono، نويسنده , , Kimihiro and Kawakami، نويسنده , , Toshihiko and Nakayama، نويسنده , , Katsuhisa and Nishino، نويسنده , , Kohei and Nakayama، نويسنده , , Takayuki and Takahashi، نويسنده , , Keisuke and Nakamura، نويسنده , , Aki and Hosokawa، نويسنده , , Takahiro، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
3590
To page
3592
Abstract
A novel catalyst system of Pd(OAc)2–HFIP induces double-bond migration of allylbenzenes under mild conditions with low catalytic loading to afford 1-propenylbenzenes. The reaction shows a unique substituent effect that is highly dependent on the distance of substituents from the allylic moiety. Thus, the reactivity of substrates bearing a methyl group is ordered in para > meta > ortho, whereas it is entirely reversed as ortho > meta > para for methoxy and chloro substituents.
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1873341
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