Title of article
Enantioselective Darzens reaction using organoselenide–lithium hydroxide complexes
Author/Authors
Watanabe، نويسنده , , Shin-ichi and Hasebe، نويسنده , , Risa and Ouchi، نويسنده , , Jun and Nagasawa، نويسنده , , Hideko and Kataoka-Shirasugi، نويسنده , , Tadashi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
5778
To page
5780
Abstract
Asymmetric Darzens reaction catalyzed by chiral selenides is described. A novel Lewis acid/Brّnsted base catalyst formed by C2 symmetric chiral selenide-bearing isoborneol skeletons, which were readily prepared from (1S)-10-camphorsulfonic acid, and LiOH promoted the reaction of phenacyl bromide with aldehydes to afford the desired trans oxiranes with up to 62% ee.
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1875267
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