• Title of article

    Preparation of mono-labelled aliphatic polyacids via isoxazole derivatives

  • Author/Authors

    Adamo، نويسنده , , Mauro F.A. and Sarti-Fantoni، نويسنده , , Piero and Chimichi، نويسنده , , Stefano and Sandrelli، نويسنده , , Alessandro، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2010
  • Pages
    3
  • From page
    6310
  • To page
    6312
  • Abstract
    A method allowing the selective oxygen labelling of aliphatic polyacids, for example, succinic and glutaric acids, is reported. This process is based on the hydrolysis of a 3-alkyl-4-nitroisoxazol-5-yl group by Na18OH and affords the products in high yields. The same procedure was applied for the preparation of labelled aliphatic carboxylic acids.
  • Keywords
    Polyfunctional scaffolds , 4-Nitroisoxazole , 18O-bilabelled carboxylates
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2010
  • Journal title
    Tetrahedron Letters
  • Record number

    1875708