Title of article
Synthesis of fused dihydropyrido[e]purines via ring closing metathesis
Author/Authors
Litinas، نويسنده , , Konstantinos E. and Thalassitis، نويسنده , , Andreas، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
3
From page
6451
To page
6453
Abstract
Ring closing metathesis (RCM) of 8,9-diallylpurines or 9-butenyl-8-vinylpurines with the Grubbs 2nd generation catalyst resulted in fused 6,9- or 8,9-dihydropyrido[e]purines, respectively. The 8,9-dialkenylpurines were prepared from 8-bromopurines after 9-alkenylation and subsequent Stille coupling at C-8 with alkenylstannanes in the presence of Pd(PPh3)4 or Pd(PPh3)2Cl2.
Keywords
Ring closing metathesis , Stille coupling , Pd(PPh3)4
Journal title
Tetrahedron Letters
Serial Year
2010
Journal title
Tetrahedron Letters
Record number
1875822
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