Title of article
An expedient atom-efficient synthesis of the cannabinoid CB1 receptor inverse agonist ibipinabant
Author/Authors
Lange، نويسنده , , Jos H.M. and Sanders، نويسنده , , Hans J. and van Rheenen، نويسنده , , Jeroen، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
1303
To page
1305
Abstract
A novel synthetic route to the highly selective and orally active cannabinoid CB1 receptor inverse agonist ibipinabant is described which combines the use of inexpensive, commercially available reagents and mild reaction conditions with a high degree of atom-efficiency. The method is expected to enable the rapid synthesis of a variety of sulfonylguanidines.
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1877236
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