Title of article
Trichlorosilyl triflate for enantioselective direct-type aldol reaction with chiral phosphine oxide
Author/Authors
Kotani، نويسنده , , Shunsuke and Aoki، نويسنده , , Shohei and Sugiura، نويسنده , , Masaharu and Nakajima، نويسنده , , Makoto، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
2834
To page
2836
Abstract
Trichlorosilyl triflate, in the presence of a chiral Lewis base catalyst, provides an effective method for the enantioselective direct-type aldol reaction of aldehydes and ketones. A chiral Lewis base induces both the production and activation of trichlorosilyl enol ether, yielding an aldol product in good yield and with high diastereo- and enantioselectivities.
Keywords
aldol reaction , Enantioselective catalysis , Trichlorosilyl triflate , Phosphine oxide , Lewis base
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878371
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