Title of article
Grignard reagent induced tandem semipinacol rearrangement/ketone addition reaction of 20S-hydroxy-5α-pregnane-16(17)-epoxide
Author/Authors
Huang، نويسنده , , Chunxi and Shi، نويسنده , , Yong and Lin، نويسنده , , Jing-Rong and Jin، نويسنده , , Rong-Hua and Tian، نويسنده , , Wei-Sheng، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
4123
To page
4125
Abstract
A Grignard reagent induced tandem semipinacol rearrangement/chelation-controlled ketone addition process, which converts 20S-hydroxy-5α-pregnane-16(17)-epoxide into an unusual C20-substituted 17S-pregnane-3S,16R,20S-triol, is described.
Keywords
Grignard reagent , Semipinacol rearrangement , Tandem reaction , Epoxide opening
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878938
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