Title of article
Palladium(0)-catalysed cross-coupling of 2-trimethylsilylpyridine with aryl halides
Author/Authors
Blakemore، نويسنده , , David C. and Marples، نويسنده , , Louise A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
4192
To page
4195
Abstract
A general method for the Hiyama coupling reaction between aryl halides and 2-trimethylsilylpyridine has been developed. These conditions have been successfully applied to the synthesis of bis-heteroaryl systems, a key disconnection for the pharmaceutical industry in the synthesis of drug-like molecules.
Keywords
fluoride , Hiyama , Copper(I) , 2-Trimethylsilylpyrdine
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1878973
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