Title of article
Rapid synthesis of 1-deoxygalactonojirimycin using a carbamate annulation
Author/Authors
Timmer، نويسنده , , Mattie S.M. and Dangerfield، نويسنده , , Emma M. and Cheng، نويسنده , , Janice M.H. and Gulab، نويسنده , , Shivali A. and Stocker، نويسنده , , Bridget L.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
4803
To page
4805
Abstract
A remarkably efficient synthesis of the biologically important iminosugar 1-deoxygalactonojirimycin (DGJ) is presented. Key to this strategy is the development of a novel carbamate annulation reaction that favours formation of a six-membered carbamate-containing piperidine skeleton over its five-membered counterpart.
Keywords
Carbamate , Iminosugar , iodocyclisation , synthetic methodology , total synthesis
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879225
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