Title of article
An intramolecular Tsuji-Trost reaction based approach to the synthesis of 6-methylene indolizidines
Author/Authors
Martin، نويسنده , , Romy E. and Polomska، نويسنده , , Marta E. and Byrne، نويسنده , , Lindsay T. and Stewart، نويسنده , , Scott G.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
4878
To page
4881
Abstract
Herein we describe the efficient stereoselective preparation of C8 substituted indolizidines bearing a 6-methylene group, from the chiral pool starting material l-proline. This synthesis, employing a Tsuji-Trost reaction as the key step, represents a potentially, efficient route to pumiliotoxin natural product epimers.
Keywords
indolizidines , Intramolecular Tsuji-Trost reaction , allylation , pumiliotoxins
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879242
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