Title of article
Au-catalyzed cyclization of allenylsilanes. Regioselective conversion to 2-amino-4-silylmethylene γ-butyrolactone
Author/Authors
Okada، نويسنده , , Takuya and Sakaguchi، نويسنده , , Kazuhiko and Shinada، نويسنده , , Tetsuro and Ohfune، نويسنده , , Yasufumi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
5740
To page
5743
Abstract
The Au(I)-catalyzed cyclization of an allenylglycine, which possessed a silyl group attached to the opposite side of the allenic terminus, occurred at the allenic center to produce the 2-amino-4-silylmethylene-substituted γ-butyrolactone 2a in a highly regio- and stereoselective manner. The presence of a silyl group at the allenic terminus is crucial for the present 5-endo-dig γ-butyrolactonization.
Keywords
Au-catalyzed cyclization , Allenylsilane , ?-Butyrolactone
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879455
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