Title of article
Microwave-assisted synthesis of N1- and C3-substituted pyrazolo[3,4-d]pyrimidine libraries
Author/Authors
Todorovic، نويسنده , , Nick and Awuah، نويسنده , , Emelia and Shakya، نويسنده , , Tushar and Wright، نويسنده , , Gerard D. and Capretta، نويسنده , , Alfredo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
5761
To page
5763
Abstract
The parallel synthesis of a library N1- and C3-substituted-pyrazolo[3,4-d]pyrimidines is described. The microwave-assisted approach involves the de novo generation of the heterocyclic scaffold, facile alkylation at N1 via either a Mitsunobu or a direct alkylation reaction and arylation at C3 via a Suzuki reaction.
Keywords
Pd-catalyzed cross coupling , 4-d]pyrimidines , Library synthesis , Microwave-assisted synthesis , Mitsunobu reaction
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879461
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