Title of article
A two-step synthesis of 1,5-disubstituted tetrazoles containing a siloxy or sulfonamide group
Author/Authors
Sarvary، نويسنده , , Afshin and Shaabani، نويسنده , , Shabnam and Shaabani، نويسنده , , Ahmad and Ng، نويسنده , , Seikweng and Zhang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
5930
To page
5933
Abstract
A simple two-step route to the synthesis of 1,5-disubstituted tetrazoles containing a β-siloxy or β-sulfonamide group is presented. The synthesis takes place via an isocyanide-based multicomponent reaction and allows incorporation of a wide variety of substitution patterns starting from commercially available reagents. This is followed by cyclization of the ketenimines with trimethylsilyl azide without using any catalyst or activation.
Keywords
5-Disubstituted tetrazole , Ketenimine , isocyanide , multicomponent , 1
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879502
Link To Document