Title of article
A novel three-step synthesis of Celecoxib via palladium-catalyzed direct arylation
Author/Authors
Gaulier، نويسنده , , Steven M. and McKay، نويسنده , , Reuben and Swain، نويسنده , , Nigel A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
6000
To page
6002
Abstract
A novel three linear step synthesis of Celecoxib was achieved in 33% overall yield via a key regioselective direct C–H arylation reaction between a 1,3-disubstituted pyrazole and an aryl bromide.
Keywords
Celecoxib , Direct arylation , Pd catalysis
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879519
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