Title of article
Synthesis of new series of iboga analogues
Author/Authors
Paul، نويسنده , , Sibasish and Pattanayak، نويسنده , , Sankha and Sinha، نويسنده , , Surajit، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
6166
To page
6169
Abstract
Synthesis of new iboga-analogues, replacing the indole ring with a benzofuran moiety has been described. Starting materials are the suitably substituted benzofuran derivatives and have been synthesized by Pd-catalyzed reactions. The conversion of endo-6-methylcarboxylate substituted dehydroisoquinuclidine to exo-isomer, a key component of iboga-alkaloids has been achieved in the presence of NaOMe in methanol under reflux conditions.
Keywords
Iboga-analogues , heteroannulation , Dehydroisoquinuclidine , Palladium-catalyst
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879559
Link To Document