Title of article
1,n-Diamines. Part 4: synthesis of 1-aryl-2-alkyl-1,4,5,6,7,8-hexahydro-1,3-diazocines
Author/Authors
Dيaz، نويسنده , , Jimena E. and Gruber، نويسنده , , Nadia and Orelli، نويسنده , , Liliana R.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
3
From page
6443
To page
6445
Abstract
In this Letter we present the synthesis of hitherto unreported 1-aryl-2-alkyl-1,4,5,6,7,8-hexahydro-1,3-diazocines 1. Cyclic amidines 1 were synthesized by PPSE promoted ring closure of N-acyl-N′-arylpentamethylenediamines 2. The cyclodehydration reaction was performed under microwave irradiation in solvent-free conditions. Precursors 2 were prepared by selective functionalization of N-arylcadaverines 3.
Keywords
Polyamine analogs , Cyclic amidines , PPSE , Medium size heterocycles , Microwaves
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879625
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