Title of article
One-pot and catalyst-free amidation of ester: a matter of non-bonding interactions
Author/Authors
Rezazgui، نويسنده , , Olivier and Boëns، نويسنده , , Benjamin and Teste، نويسنده , , Karine and Vergnaud، نويسنده , , Julien and Trouillas، نويسنده , , Patrick and Zerrouki، نويسنده , , Rachida، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
6796
To page
6799
Abstract
This paper describes a one-pot procedure for acetamide synthesis directly from amines and pyrimidine ester, without any catalyst or coupling agents. The inexpensive and simple reaction conditions are the most important features of this amidation. This reaction was performed with various amines, showing that long range stabilizing interactions (H-bonding and π-stacking) are the driving force for chemoselectivity.
Keywords
Uracil acetate , DFT calculations , Amidation , Non-bonding interactions
Journal title
Tetrahedron Letters
Serial Year
2011
Journal title
Tetrahedron Letters
Record number
1879714
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