Title of article
One-pot synthesis of [1,2,3]triazole-fused pyrazinopyridazindione tricycles by a ‘click and activate’ approach
Author/Authors
Qian، نويسنده , , Wenyuan and Winternheimer، نويسنده , , David and Amegadzie، نويسنده , , Albert J. Allen، نويسنده , , Jennifer، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
271
To page
274
Abstract
Substituted [1,2,3]triazole-fused pyrazinopyridazindione tricycles were synthesized in a four-component, stepwise condensation. The key step in this one-pot process was a thermal [3+2] triazole formation which activated the adjacent position and set the stage for a subsequent tandem nucleophilic aromatic substitution/cyclization sequence.
Keywords
Activation of neighboring group , Tandem nucleophilic aromatic substitution/cyclization , Multiple component reactions , Triazole-fused pyrazinopyridazindione
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1879932
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