Title of article
A convenient one-pot synthesis of 1-aryl-substituted 2H-isoquinolin-3-ones
Author/Authors
Méndez، نويسنده , , Leticia J. and Cلnepa، نويسنده , , Alicia S. and Gonzلlez، نويسنده , , M. Gloria and Bravo، نويسنده , , Rodolfo D.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
688
To page
690
Abstract
The synthesis of 1-aryl-substituted 2H-isoquinolin-3-ones is studied from 2-cyanomethylbenzoic acid and substituted benzenes via Friedel–Crafts acylation and intramolecular cyclization of 2-acylphenylacetonitriles formed in a one-pot method using sulfated zirconia as catalysts. Short reaction times, simplicity of operation, and easy work-up are some advantages of this method.
Keywords
Intramolecular cyclization , 1-Aryl-substituted 2H-isoquinolin-3-ones , one-pot synthesis , Sulfated zirconia , 2-Acylphenylacetonitriles
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880070
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