Title of article
A route to selective functionalization of polyhydroxypyrrolidines
Author/Authors
Sousa، نويسنده , , Carlos A.D. and Rizzo-Aguiar، نويسنده , , Fabio and Vale، نويسنده , , M. Luيsa C. and Garcيa-Mera، نويسنده , , Xerardo and Caamaٌo، نويسنده , , Olga and Rodrيguez-Borges، نويسنده , , José E.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
1029
To page
1032
Abstract
A route to selective functionalization of polyhydroxypyrrolidines is described. The method is based on orthogonal protection/deprotection along the process of synthesis of the referred pyrrolidines, which consist in hydroxylation of the double bond of 2-azabicyclo[2.2.1]hept-5-enes followed by its oxidative cleavage and in situ reduction of the intermediate dialdehyde. The synthesis of a novel N-hydroxypyrrolidine is also described.
Keywords
Polyhydroxypyrrolidines , Orthogonal protection , Selective Functionalization , Azasugar
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880178
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