Title of article
Synthesis of chiral 1,2,3-triols via organocatalyzed α-hydroxylation of protected β-hydroxyaldehydes
Author/Authors
Colin، نويسنده , , Olivier and Hermange، نويسنده , , Philippe and Thomassigny، نويسنده , , Christine and Greck، نويسنده , , Christine، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
1085
To page
1088
Abstract
Protected 1,2,3-triols were prepared by organocatalytic α-hydroxylation of β-hydroxyaldehydes followed by in situ reduction. All diastereoisomers were obtained with correct yields and good to excellent de. The absolute configurations of the new asymmetric centers were confirmed by derivatization into the corresponding epoxide.
Keywords
1 , 2 , 3-Triols , hydroxylation , organocatalysis , Enantioselectivity , hydroxyaldehydes
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880193
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