Title of article
Synthesis and antitumour activity of inositol phosphonate analogues
Author/Authors
Song، نويسنده , , Fanbo and Zhang، نويسنده , , Jing and Cui، نويسنده , , Quanbin and Wang، نويسنده , , Ting and Chen، نويسنده , , Wenbin and Li، نويسنده , , Luyuan and Xi، نويسنده , , Zhen، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
1102
To page
1104
Abstract
Inositol phosphates regulate important biological functions in intracellular signal transduction events. Phosphonates, because of the stability towards the action of phosphatases, were extensively used to replace phosphates. We herein reported the synthesis of inositol phosphonate analogues using myo-inositol as the starting material, and found that two of phosphonate analogues exhibited relative good cytotoxic activity against non-small cell lung cancer (NSCLC) cell line A549.
Keywords
Inositol phosphonate , Inositol phosphate , Anticancer agents , NSCLC
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1880197
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