Title of article
Rapid, clean and efficient one-pot synthesis of thiopyrano[2,3-b]quinolines via domino Michael addition/cyclization reactions
Author/Authors
Singh، نويسنده , , Bhawana and Chandra، نويسنده , , Atish and Asthana، نويسنده , , Mrityunjaya and Singh، نويسنده , , Radhey M.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
3242
To page
3244
Abstract
Rapid and efficient one-pot synthesis of thiopyrano[2,3-b]quinolines is described from the reaction of 3-formyl-quinoline-2-thiones with acrylonitrile using economical organic base Et3N at room temperature. The reaction proceeded smoothly via domino Michael addition/cyclization reactions and did not require dry solvent, inert atmosphere and column chromatography purifications.
Keywords
Domino reaction , Michael addition/cyclization , 3-Formyl-quinoline-2-thiones , 3-b]quinolines , Et3N
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881018
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