Title of article
Asymmetric total synthesis of (S)-dapoxetine
Author/Authors
Kim، نويسنده , , Sun Joo and Jeon، نويسنده , , Tae Hong and Min، نويسنده , , Im Sook and Kim، نويسنده , , In Su and Jung، نويسنده , , Young Hoon، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
3680
To page
3682
Abstract
A concise asymmetric total synthesis of (S)-dapoxetine from commercially available 3-chloropropiophenone is described. The key step includes a highly stereoselective amination of chiral benzylic ether, with the retention of stereochemistry, using chlorosulfonyl isocyanate.
Keywords
Dapoxetine , Chlorosulfonyl isocyanate , amination , asymmetric
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881208
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