• Title of article

    Asymmetric total synthesis of (S)-dapoxetine

  • Author/Authors

    Kim، نويسنده , , Sun Joo and Jeon، نويسنده , , Tae Hong and Min، نويسنده , , Im Sook and Kim، نويسنده , , In Su and Jung، نويسنده , , Young Hoon، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2012
  • Pages
    3
  • From page
    3680
  • To page
    3682
  • Abstract
    A concise asymmetric total synthesis of (S)-dapoxetine from commercially available 3-chloropropiophenone is described. The key step includes a highly stereoselective amination of chiral benzylic ether, with the retention of stereochemistry, using chlorosulfonyl isocyanate.
  • Keywords
    Dapoxetine , Chlorosulfonyl isocyanate , amination , asymmetric
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2012
  • Journal title
    Tetrahedron Letters
  • Record number

    1881208