Title of article
One-pot method for α-phenylation of ketones using isoxazolidine and triphenylaluminum
Author/Authors
Miyoshi، نويسنده , , Tetsuya and Sato، نويسنده , , Shohei and Tanaka، نويسنده , , Hiroya and Hasegawa، نويسنده , , Chihiro and Ueda، نويسنده , , Masafumi and Miyata، نويسنده , , Okiko، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
4188
To page
4191
Abstract
The efficient one-pot umpolung α-phenylation of ketones via N-alkenylisoxazolidine is described. When the various ketones are treated with triphenylaluminum prepared from phenylmagnesium chloride and AlCl3 in the presence of isoxazolidine, the desired products are obtained in good to moderate yield. This method is equivalent to a direct α-arylation reaction of carbonyl groups.
Keywords
umpolung , Ketone , one-pot reaction , Enamine , Phenylmagnesium chloride
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881448
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