Title of article
Palladium-catalyzed synthesis of 4-alkoxycarbonyl-3,4-dihydroisoquinolin-1(2H)-ones
Author/Authors
Okuro، نويسنده , , Kazumi and Alper، نويسنده , , Howard، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
4816
To page
4818
Abstract
Palladium-catalyzed intermolecular cyclocarbonylation of diethyl (2-iodoaryl)malonates with N-tosylimines produces 4-ethoxycarbonyl-3,4-dihydroisoquinolin-1(2H)-ones in moderate to good yields. This reaction is highly stereoselective. This protocol involves Mannich addition, and subsequent cyclocarbonylation.
Keywords
Mannich addition , 4-Dihydroisoquinolin-1(2H)-ones , 3 , PALLADIUM , cyclocarbonylation
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1881711
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