Title of article
Indium trichloride catalyzed three component one-pot route to 1-hydroxymethyl-3-aminomethyl indoles
Author/Authors
Acharya، نويسنده , , Chiranjit and Dey، نويسنده , , Sumit and Jaisankar، نويسنده , , Parasuraman، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
5548
To page
5551
Abstract
A one-pot synthesis of 1-hydroxymethyl-3-aminomethyl indoles 3 could be achieved in excellent yield by reacting indoles 1 with formaldehyde and secondary amines 2 in the presence of molecular sieves (3 Å) and catalytic amount of InCl3 (10 mol %) in 1,4-dioxane at room temperature for 3–5 h.
Keywords
indium trichloride , 1-Hydroxymethyl-3-aminomethyl indoles , Formaldehyde , Diethyl amine , Piperidine
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1882267
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