Title of article
New potent vinca alkaloids resulting from an unexpected isomerization
Author/Authors
Ngo، نويسنده , , Quoc Anh and Roussi، نويسنده , , Fanny and Thoret، نويسنده , , Sylviane and Guéritte، نويسنده , , Françoise، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
5821
To page
5823
Abstract
Four new vinca alkaloids have been elaborated, using an unexpected isomerization and formation of stable enammoniums in very mild conditions. They are cytotoxic on a sub-micromolar range and inhibit microtubule assembly.
Keywords
Enammoniums , Vinca alkaloids , Ammonium salts , Tubulin
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1882432
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