Title of article
Three-component reactions of CF3-substituted boranes, ethyl diazoacetate and imines
Author/Authors
Elkin، نويسنده , , Pavel K. and Levin، نويسنده , , Vitalij V. and Dilman، نويسنده , , Alexander D. and Struchkova، نويسنده , , Marina I. and Arkhipov، نويسنده , , Dmitry E. and Korlyukov، نويسنده , , Alexander A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
6216
To page
6218
Abstract
Aryl(methoxy)(trifluoromethyl)boranes, generated in situ, readily react with ethyl diazoacetate and N-(4-methoxyphenyl)imines to give derivatives of β-amino acids. In this process, the electron-deficient borane reacts with the diazo compound followed by trapping of the intermediate boron enolate by the imine. The final products are predominantly produced as syn isomers.
Keywords
trifluoromethylation , multicomponent reaction , imines , boronic esters , Boranes , Diazocarbonyl compounds
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1882656
Link To Document