Title of article
Cinchona alkaloids induce asymmetry in the insertion reaction of thermally generated carbenes into N−H bonds
Author/Authors
Saito، نويسنده , , Hiroaki and Morita، نويسنده , , Daisuke and Uchiyama، نويسنده , , Taketo and Miyake، نويسنده , , Muneharu and Miyairi، نويسنده , , Shinichi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
3
From page
6662
To page
6664
Abstract
Ammonium ylides generated in situ from phenyldiazoacetates and anilines undergo asymmetric N−H insertion reactions catalyzed by cinchona alkaloids (1 mol %), affording phenylglycines up to 74% ee.
Keywords
asymmetric synthesis , Carbene , N?H insertion reaction , organocatalysis , Thermolysis
Journal title
Tetrahedron Letters
Serial Year
2012
Journal title
Tetrahedron Letters
Record number
1882858
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