• Title of article

    Familial primary mediastinal nonseminomatous germ-cell tumors

  • Author/Authors

    Marti، نويسنده , , Adina and Culine، نويسنده , , Stéphane and Carde، نويسنده , , Patrice and Paugam، نويسنده , , Bertrand and Fizazi، نويسنده , , Karim، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2004
  • Pages
    4
  • From page
    421
  • To page
    424
  • Abstract
    In this article, we describe the case of 4 brothers, 2 of which had primary mediastinal nonseminomatous germ cell tumors (PMNSGCT), while the other 2 had benign mediastinal disease. We discuss the relationship between these diseases of the mediastinum and the thymic microenvironment. Additionally, we suggest that a genetic predisposition for germ-cell tumors (GCT) may be involved since the parents were relatives.
  • Keywords
    Primary mediastinal nonseminomatous germ cell tumor , genetics , Thymus microenvironment , chemotherapy
  • Journal title
    Urologic Oncology
  • Serial Year
    2004
  • Journal title
    Urologic Oncology
  • Record number

    1883305