Title of article
Microwave assisted Westphal condensation and its application to synthesis of sempervirine and related compounds
Author/Authors
Chinta Rao، نويسنده , , T.S. and Saha، نويسنده , , Sanjay and Raolji، نويسنده , , Gajendra B. and Patro، نويسنده , , Balaram and Risbood، نويسنده , , Prabhaker and Difilippantonio، نويسنده , , Michael J. and Tomaszewski، نويسنده , , Joseph E. and Malhotra، نويسنده , , Sanjay V.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
487
To page
490
Abstract
A concise synthesis of a potent lead in anticancer therapeutics, sempervirine, was achieved by one pot Westphal condensation, ester hydrolysis, and decarboxylation under microwave irradiation. The method was extended to the synthesis of several similar heterocycles.
Keywords
Westphal condensation , Microwave assisted , DNA intercalator , Sempervirine , Antiproliferative agent
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1883530
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