Title of article
Palladium(II)-catalyzed asymmetric cycloisomerization of enynes for axially chiral biaryl construction
Author/Authors
Kadoya، نويسنده , , Nobuaki and Murai، نويسنده , , Masato and Ishiguro، نويسنده , , Masako and Uenishi، نويسنده , , Jun’ichi and Uemura، نويسنده , , Motokazu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
512
To page
514
Abstract
Palladium(II)-catalyzed asymmetric cycloisomerization of enynes with (R)-binap gave axially chiral biaryls with up to 99%ee. The reactivity and enantioselectivity depended on the nature and position of substituent of the arene ring. The enynes with ortho methoxy arene at alkyne terminus gave chiral biaryls with good enantioselectivity.
Keywords
Axially chiral biaryl , Asymmetric cycloisomerization , Enyne compounds , palladium catalyst
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1883537
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