Title of article
Lewis acid-catalyzed Csp3–H functionalization of methyl azaarenes with α-trifluoromethyl carbonyl compounds
Author/Authors
Graves، نويسنده , , Vincent B. and Shaikh، نويسنده , , Abid، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
695
To page
698
Abstract
A Lewis acid promoted Csp3–H bond functionalization of methyl azaarenes with α-trifluoromethylated carbonyl compounds is described. Catalytic amounts of Yb(OTf)3 provided a straightforward access to the corresponding trifluoromethylated alcohols in excellent yields up to 94% under mild reaction conditions.
Keywords
Azaarenes , C–H functionalization , Trifluoromethyl ketone , Catalysis , Lewis acid
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1883614
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