Title of article
The pipecolic linker—an acid-labile handle for derivatization of secondary amines on a solid-support. Part 3
Author/Authors
Zajdel، نويسنده , , Pawe? and Masurier، نويسنده , , Nicolas and Canale، نويسنده , , Vittorio and Verdie، نويسنده , , Pascal and Amblard، نويسنده , , Muriel and Paw?owski، نويسنده , , Maciej and Martinez، نويسنده , , Jean and Subra، نويسنده , , Gilles، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
5
From page
998
To page
1002
Abstract
Herein, we demonstrate the versatility of the pipecolic linker for the structural diversification of secondary amines with potential CNS activity. The solid-phase methods elaborated involved N1-indole sulfonylation, nitroindole and nitroarene reduction, and microwave-assisted Buchwald–Hartwig N-arylation.
Keywords
Indole sulfonamide , N-Arylation , Nitro reduction , solid-phase synthesis , Pipecolic linker
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1883740
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