Title of article
Regio- and stereoselective preparation of (Z)-silyl enol ethers by three-component coupling using α,β-unsaturated acylsilanes as core building blocks
Author/Authors
Tsubouchi، نويسنده , , Akira and Sasaki، نويسنده , , Natsuki and Enatsu، نويسنده , , Shouko and Takeda، نويسنده , , Takeshi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
1264
To page
1267
Abstract
Based on the conjugate addition–silyl migration–alkylation strategy, (Z)-silyl enol ethers possessing a stereocenter at the γ-position were prepared with complete regio- and stereoselectivity by three-component coupling of α,β-unsaturated acylsilanes, Grignard reagents (or cuprates)/copper(I) tert-butoxide, and organic halides.
Keywords
copper(I) tert-butoxide , conjugate addition , Silyl enol ethers , silyl migration , three-component coupling
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1883891
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