Title of article
Facile synthesis of diverse isoindolinone derivatives via Ugi-4CR followed by Cu-catalyzed deamidative C(sp2)–C(sp3) coupling
Author/Authors
Tyagi، نويسنده , , Vikas and Khan، نويسنده , , Shahnawaz and Chauhan، نويسنده , , Prem M.S. Chauhan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
6
From page
1279
To page
1284
Abstract
The present work highlights a synthetic approach to the diverse isoindolinone derivatives using Ugi-4CR followed by a Cu-catalyzed deamidative C–C coupling reaction.
wo-step sequence tolerates a broad range of amines, aldehydes, and isocyanides as starting materials for Ugi-4CR products to provide medicinally relevant isoindolinone derivatives in moderate to good yields.
Keywords
multicomponent reactions , Copper catalysis , Isoindolenone , Ugi reaction , C–C coupling
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1883897
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