Title of article
Metal-mediated reactions of aryl isocyanates with dimethoxycarbene to form isatin derivatives
Author/Authors
Rigby، نويسنده , , James H. and Brouet، نويسنده , , Stephanie A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
2542
To page
2545
Abstract
Hydantoin derivatives have been established as the observed product in the reaction of aryl isocyanates with dimethoxycarbene. A change in the reactivity profile of dimethoxycarbene with aryl isocyanates was observed upon the addition of a metal species. Methodology has been developed in which the outcome of nucleophilic carbene reactions with isocyanates can be controlled with simple changes to reaction conditions.
Keywords
Nucleophilic carbene , Isatin , Electrophilic aromatic substitution , dimethoxycarbene , Hydantoin , Isocyanate
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884425
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