Title of article
Asymmetric organocatalytic Michael–hemiacetalization reaction: access to chiral spiro cis-δ-lactones by in situ oxidation of spiro δ-lactols
Author/Authors
Wei، نويسنده , , Mo-Hui and Zhou، نويسنده , , Yi-Rong and Gu، نويسنده , , Liang-Hu and Luo، نويسنده , , Fan and Zhang، نويسنده , , Fang-Lin، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
2546
To page
2548
Abstract
Asymmetric tandem Michael–hemiacetalization reaction between 1-nitromethylcycloalkanol and α,β-unsaturated aldehydes was investigated, which provided an efficient and facile synthesis for spiro cis-δ-lactones by in situ oxidation of spiro δ-lactols in good overall yields with high to excellent enantioselectivities and diastereoselectivities.
Keywords
organocatalysis , Asymmetric catalysis , Cascade reaction , Spirolactone
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884427
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