Title of article
Synergistic effect of achiral quaternary ammonium salt on asymmetric additions of diethylzinc to aldehydes
Author/Authors
Zong، نويسنده , , Hua and Huang، نويسنده , , Huayin and Bian، نويسنده , , Guangling and Song، نويسنده , , Ling، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
2722
To page
2725
Abstract
Our investigation has shown that achiral quaternary ammonium salt has a significant synergistic effect on the asymmetric additions of diethylzinc to aldehydes catalyzed by chiral phosphoramide–Zn(II) complex. The addition of 10 mol % NBu4X can dramatically reduce the loading amount of chiral ligand without sacrificing the excellent reactivity and enantioselectivity of the asymmetric reaction.
Keywords
Synergistic effect , Quaternary ammonium salt , asymmetric addition
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884502
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