Title of article
Regio- and stereoselective synthesis of 1-(1-halovinyl)-1H-indoles from 1-ethynyl-1H-indoles with in situ generated HX
Author/Authors
Sato، نويسنده , , Akihiro H. and Ohashi، نويسنده , , Kazuhiro and Ito، نويسنده , , Kouhei and Iwasawa، نويسنده , , Tetsuo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
2878
To page
2881
Abstract
A facile approach to 1-(1-halovinyl)-1H-indoles from readily accessible 1-ethynyl-1H-indoles with in situ generated HX is described. The simple protocol enables a regio- and stereoselective hydrohalogenation to the triple bonds in gram-scale, and provides a general entry for novel N-alkenylindole derivatives.
Keywords
iodotrimethylsilane , Haloenamides , Hydroiodation , indole , Ynamides
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884571
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