Title of article
An effective one-pot conversion of acid chlorides to aldehydes and ketones
Author/Authors
Park، نويسنده , , Jae Kyo and Shin، نويسنده , , Won Kyu and An، نويسنده , , Duk Keun، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
5
From page
3199
To page
3203
Abstract
Aldehydes and ketones were synthesized from their respective acid chlorides via a one-pot protocol. Morpholine amide intermediates that were readily prepared by the aminolysis of various acid chlorides with diisobutyl(morpholino)aluminum smoothly reacted with the reducing agent LDBMA and the organolithium reagents under mild reaction conditions (0 °C), giving almost excellent product yields of up to 95%.
Keywords
Diisobutylaluminum hydride (DIBALH) , Morpholine amide , aldehyde , Acid chloride , Ketone
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884700
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